The terms milk thistle and silymarin are often used interchangeably. The following conditions are contraindicated with this drug. Tajmohammadi A, Razavi BM, Hosseinzadeh H. Therefore, it is not known whether milk thistle or silymarin should be used to treat cirrhosis. Silymarin is believed to have antioxidant properties. When looking at Milk Thistle itself (prior to any extraction), the fruits or thistles contain: Silymarin at 1.5-3% of dry weight (to be elucidated later) [2] Silyhermin and both Neosilyhermin A and B [2]; Protein and Mucilage (taking up 25-30% of the herb by dry weight) [2] Quercetin and the dihydro varient known as Taxifolin [2]; Kaempferol, Dihydrokaempferol, and the 7-glucoside and 3 . According to researchers, these findings suggest that silymarin may improve diabetes symptoms like oxidative stress and inflammation. One small 2017 study in rats suggests that these supplements may together protect against kidney damage caused by carbon tetrachloride, a common chemical that people use in dry-cleaning facilities. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product. Milk thistle: effects on liver disease and cirrhosis and clinical adverse effects: summary. 2012;308(3):274-82. doi:10.1001/jama.2012.8265. Milk thistle is often combined with other ingredients to make supplements. Canada residents can call a provincial poison control center. Soy Protein Vs. Whey Protein: Pros And Con Soy Protein Vs. Whey Protein: Pros And Cons + Which Is Better. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Milk thistle had no effect on any of the drugs. Milk thistle is generally thought to be safe, but you still may experience side effects when taking it. Biomed Res Int. Steep milk thistle tea bags or loose-leaf milk thistle tea in hot water. He specializes Professional Certificate In Food, Nutrition & Health. Properly discard this product when it is expired or no longer needed. But it may be a helpful complementary treatment to try if a healthcare professional approves it. Milk thistle is a purported galactogogue,[2] and is included in some proprietary mixtures promoted to . This may help ease symptoms from liver . The effects of milk thistle (Silybum marianum) on human cytochrome P450 activity. Milk thistle may lower blood sugar levels in people with type 2 diabetes. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Hence, limit its usage if you experience any adverse reactions. Does Milk Thistle Capsule interact with other medications? For centuries, this herb has been used in fighting hangovers (9). Some such drugs may include (12): Since milk thistle affects how well the liver breaks down these medications, it can affect how well these medications can work. She has 14 years of experience in Clinical Nutrition as well as teaching Nutrition and Dietetics to undergraduate and postgraduate students. Finally, those with hormone-sensitive conditions, including certain cancers, may need to avoid using milk thistle. These combination supplements may list health claims on the label. Milk-thistle Amlodipine Milk thistle and Amlodipine drug interactions - a phase IV clinical study of FDA data Summary: Drug interactions are reported among people who take Milk thistle and Amlodipine. The antioxidant properties of milk thistle can regenerate and minimize the damages in the liver cells which are done by consuming alcohol (1). It could help the body fight off infection as well as reduce chronic inflammation produced by the immune system. Milk thistle side effects (more detail) Milk thistle for alcoholic and/or hepatitis B or C liver diseases--a systematic Cochrane hepato-biliary group review with meta-analyses of randomized clinical trials. Milk thistle is an herbal remedy with rich plant compounds. 2014;2014:941085. doi:10.1155/2014/941085. Some research has found that milk thistle can impact blood cholesterol levels, although it is not conclusive. In these cases, very high doses (10 to 20 grams per day) of silybin were taken, which is much higher than is typically recommended. The name "milk thistle" derives from a feature of the leaves, which are prominently banded with splashes of white. Moderately clinically significant. Several studies have suggested that milk thistle may be beneficial for people with type 2 diabetes. Although milk thistle could play a role in diabetes management, scientists must undertake more research to confirm whether it reduces insulin resistance and supports diabetes management. Agency for Healthcare Research and Quality (US); 2000. Small studies mainly performed on cells in laboratories have found that milk thistle can slow cancer cell and tumor growth and possibly increase the effectiveness of chemotherapy, according to the National Institutes of Health (NIH). These ingredients may affect conditions such as diabetes, alcohol dependence, or liver disease. Soleimani V, Delghandi PS, Moallem SA, Karimi G. Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review. Yes, you can drink alcohol while taking milk thistle. MNT is the registered trade mark of Healthline Media. Herbal product use by persons enrolled in the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. Seeff, L.; Curto, T.; Szabo, G. et al. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox. Thank you, {{form.email}}, for signing up. Milk thistle may help strengthen a persons immune response. Learn, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Salmi, H. and Sarna, S. Effect of silymarin on chemical, functional, and morphological alterations of the liver. Milk thistle is native to the Mediterranean region. Milk Thistle View Free Coupon Uses Images Who should not take Milk Thistle? To establish that the product manufacturers addressed safety and efficacy standards, we: We do the research so you can find trusted products for your health and wellness. It is unknown if this product passes into breast milk. The active ingredient in milk thistle is called silymarin. Does Milk Thistle Capsule interact with other drugs you are taking? He graduated from SRM University, Chennai, and has a Professional Certificate in Food, Nutrition & Research from Wageningen University. Liver cleanses promise to rid the body of toxins and impurities, but are controversial because there is little science to support their use. People with diabetes should use caution. 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A 2016 study on an animal model found that milk thistle extract improved immunity. Hepatology. Dupuis ML, Conti F, Maselli A, et al. 1997-. Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider. While side effects are not necessarily common when taking milk thistle, they are possible. Other studies looking at milk thistle for cirrhosis have found conflicting results. If you buy through links on this page, we may earn a small commission Heres our process. This is not a complete list of possible side effects. Yes, you can take milk thistle long term. Brittany Lubeck, RD, is a nutrition writer and registered dietitian with a master's degree in clinical nutrition. You may report side effects to FDA at 1-800-FDA-1088. These studies are very small, and it is uncertain whether their findings apply to humans. Milk thistle (Silybum marianum) is a herb loaded with antioxidants and is known for its anti-inflammatory properties. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial, Silymarin in type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials, Effects and tolerance of silymarin (milk thistle) in chronic hepatitis C virus infection patients: a meta-analysis of randomized controlled trials, The Natural agonist of estrogen receptor silibinin plays an immunosuppressive role representing a potential therapeutic tool in rheumatoid arthritis, Silybin and the liver: from basic research to clinical practice, Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review, The therapeutic potential of milk thistle in diabetes, Effect of curcumin supplementation on disease severity in patients with liver cirrhosis: a randomized controlled trial, Effects of vitamin E on chronic hepatitis C genotype 3: a randomized, double-blind, placebo-controlled study, Resveratrol for the management of diabetes and its downstream pathologies, Milk thistle: effects on liver disease and cirrhosis and clinical adverse effects: summary. We know little about whether milk thistle is effective in people, as only a few well-designed clinical studies have been conducted. Kazazis CE, Evangelopoulos AA, Kollas A, Vallianou NG. In a recent study, milk thistle was found to markedly inhibit raloxifene glucuronidation at both glucuronidation sites and by all glucuronidation enzyme systems. He has been in the digital media field for over eight years. Current studies on milk thistle use a wide range of doses. In this way, milk thistle may help improve cognition and treat degenerative conditions that affect the mind. Rev Diabet Stud. Mothers who used milk thistle to boost their milk production reported unwanted weight gain along with irritability and nausea (16). Keep supplements in areas out of the reach of pets and children. An older study found that milk thistle extract had a positive effect on immune response in humans. Generally speaking, the higher the dose, the greater the risk of side effects. There are other supplements that work similarly to milk thistle. If any of these effects last or get worse, tell your doctor or pharmacist promptly. 2018;9:1903. doi:10.3389/fimmu.2018.01903. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Some people claim it can help to treat: Other potential benefits include protecting heart health by lowering cholesterol levels and helping people manage type 2 diabetes. These reactions may occur if you have an allergy to milk thistle. Merlin Annie Raj is a Registered Dietitian based out of Hyderabad, India. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Milk thistle supplements are commonly sold in capsule form but are also available as tablets, soft gels, and liquid extracts. Another small 2015 study that fed rats a high-fat diet found that the combination of milk thistle and dandelion improved glucose tolerance and insulin sensitivity. JAMA. Its not known whether milk thistle is helpful for other conditions. A small number of studies have suggested that milk thistle extract might be beneficial for diabetes, but the conclusions about its effectiveness are not definite. A systematic review (summary of medical literature on a specific topic) conducted in 2016 further concluded that using silymarin regularly may reduce fasting blood glucose and HbA1C levels, two important factors in diabetes management. Hepatology. Nouri-Vaskeh M, Malek Mahdavi A, Afshan H, Alizadeh L, Zarei M. Effect of curcumin supplementation on disease severity in patients with liver cirrhosis: a randomized controlled trial. Researchers also found in another study that milk thistle had antioxidant and anti-aging effects on human skin cells in a laboratory environment. No supplement is intended to treat, cure, or prevent disease. Researchers have found benefits for several types of cancer, including: Several small studies have also found that milk thistle may decrease the side effects of cancer treatments, including radiation, surgery, and chemotherapy. Avoid combinations; the risk of the interaction outweighs the benefit. We comply with the HONcode standard for trustworthy health information. The active ingredient in milk thistle, silymarin, acts as an antioxidant by reducing free radical production. Other potential benefits include . All rights reserved. If you have any questions, ask your doctor or pharmacist. Its seed might protect liver cells from toxic chemicals and drugs. The most common use of milk thistle is for liver problems. Voroneanu L, Nistor I, Dumea R, Apetrii M, Covic A. Silymarin in type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials. Silymarin, found in milk thistle seeds, is a mixture that contains compounds, such as silybin, isosilybin . Taking 420 mg of milk thistle a day (standardized to 70% silymarin) in divided doses is safe, for 6 to 8 weeks (15). Milk thistle may help to stop the spread of certain types of cancer. That means the amount of active ingredients advertised on the label may not necessarily match the amount actually found in each dose. More study is needed to confirm this. Although rare, milk thistle may trigger a number of common and mild side effects. Check with your pharmacist for more details about the brand you use.The FDA has not reviewed this product for safety or effectiveness. Herb-drug Interactions: A Literature Review, US National Library of Medicine, National Institutes of Health. 2007;2007(4):CD003620. (2021). Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Fried, M.; Navarro, V.; Afdhal, N. et al. Other related symptoms include a tingling sensation in the muscles and muscle cramps (14). Effect of continuous silymarin administration on oral talinolol pharmacokinetics in healthy volunteers. If left untreated, anaphylaxis can lead to shock, coma, cardiac or respiratory failure, or even death. Milk thistle is available as a supplement from many health food stores. Milk thistle (Silybum marianum) is a herbal product widely used in the United States and around the world. Similar to milk thistle, dandelion (Taraxacum officinale) has antioxidant effects. Milk thistle is also available as a tea. Also known as Mary thistle or holy thistle, milk thistle grows in Mediterranean countries and people use it to make natural remedies. Front Immunol. Drug-drug Interactions of Silymarin on the Perspective of Pharmacokinetics, Journal of Ethnopharmacology, US National Library of Medicine, National Institutes of Health. Hence, stay safe and avoid use. Eighteen clinical trials of 1,088 participants were assessed. Milk thistle: early seeds of potential, The Lancet Oncology, US National Library of Medicine, National Institutes of Health. J Diabetes Res. Milk thistle could play an essential role in supporting bone health. Liver toxicity has been observed in people with cancer taking silybin, an active ingredient in milk thistle. Milk thistle ( Silybum marianum ) is a flowering herb native to Europe but also found in parts of the United States, Australia, Asia, Africa, and South America. Call your doctor for medical advice about side effects. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Take charge of your healthtalk with your health care providers about any complementary health approaches you use. National Center for Complementary and Integrative Health. The extract of the seeds of milk thistle contains a number of substances, collectively called silymarin. Call your doctor for medical advice about side effects. Content is best viewed in IE9 or above, Firefox and Google Chrome browser. Wu J-W, Lin L-C, Tsai T-H. Drugdrug interactions of silymarin on the perspective of pharmacokinetics. milk thistle. It is possible to take too much milk thistle. Common side effects of milk thistle may include: indigestion, bloating, gas, stomach pain; diarrhea; or. It is not intended to substitute for the medical expertise and advice of your health care provider(s). Toxicity is also possible if too much milk thistle is taken. Herbal product use by persons enrolled in the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. [Database subscription]. (2021). The name milk thistle is associated with the legend of Mother Mary. Effect of silymarin on biochemical indicators in patients with liver disease: systematic review with meta-analysis. Last medically reviewed on December 17, 2021. Evidence and risks, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, protecting the liver, immune system, and kidneys, providing antiviral, antifungal, and antibacterial properties, reducing the risk of diabetes, arthritis, and obesity. Learn more about the other negative effects of this herb and what research says about them. The following two tabs change content below. Include all brand names and combination drug names. 2015;22(2):290-6. doi:10.1016/j.phymed.2014.12.010. 3. Some, but not all, milk thistle supplements are vegan. Therefore, it is important to talk to your healthcare provider about any supplements you plan to take and to check in about any potential interactions with other supplements or medications. Silymarin in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Rambaldi, A.; Jacobs, B.; Iaquinto G, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C liver diseases--a systematic Cochrane hepato-biliary group review with meta-analyses of randomized clinical trials. ), SAGE Journals. A service of the National Library of Medicine, PubMed contains publication information and (in most cases) brief summaries of articles from scientific and medical journals. Researchers found silymarin stimulated the immune system. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. High cholesterol can lead to problems with heart health and increase a persons chance of stroke. He has written over 300 articles about ingredients and their benefits for the skin, hair, and health. Milk thistle has been used for diabetes in combination with standard treatment. You may report side effects to FDA at 1-800-FDA-1088. Find out more. Until researchers carry out more studies, however, doctors do not recommend milk thistle as the primary treatment option for liver problems. We encourage you to discuss any decisions about treatment or care with your health care provider. Follow all directions on the product package. Talk with your healthcare provider before starting milk thistle to make sure it is the right supplement for you. Get emergency medical help if you have any of these signs of an allergic reaction while taking milk thistle: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Sebagai suplemen makanan, minum 1-2 kapsul setiap hari sebaiknya dengan makanan atau seperti . Silybum marianum is a species of thistle.It has various common names including milk thistle, blessed milkthistle, Marian thistle, Mary thistle, Saint Mary's thistle, Mediterranean milk thistle, variegated thistle and Scotch thistle (though not to be confused with Onopordum acanthium or Cirsium vulgare).This species is an annual or biennial plant of the family Asteraceae. Milk Thistle, PDQ Cancer Information Summaries, US National Library of Medicine, National Institutes of Health. Milk thistle has a range of potential health benefits due to its active ingredient, silymarin, which is an antioxidant. We explore the potential health benefits of milk thistle below. Regardless, interactions are still possible. Milk thistle may produce allergic reactions, which tend to be more common among people who are allergic to plants in the same family (for example, ragweed, chrysanthemum, marigold, and daisy). Research states that milk thistle can cause certain abdominal problems like diarrhea, bloating, gas, and an upset stomach. However, many of these potential benefits are not backed by science. Milk Thistle; Silybum marianum; St. Mary's Thistle. Enter other medications to view a detailed report. Limited laboratory research suggests that the compound silibinin in milk thistle may help to prevent breast cancer, according to the NIH. We include products we think are useful for our readers. He has been in the digital media field for over eight years. If it is near the time of the next dose, skip the missed dose. nausea, loss of appetite. This publication is not copyrighted and is in the public domain. Effects of Silybum marianum (L.) Gaertn. Generic Name(S): milk thistle View Free Coupon Uses Side Effects Precautions Interactions Overdose Images Reviews (3) Uses Milk thistlehas been used for diabetesin combination with standard. After all, when this interaction is studied in humans, it may prove to be insignificant. Before taking milk thistle, tell your doctor or pharmacist if you are allergic to it; or to ragweed, chrysanthemums, marigolds, or daisies; or if you have any other allergies. 2014;10(1):31-35. doi:10.17925/EE.2014.10.01.31. For an electronic version of this article, including references, if any, visit www.hanstenandhorn.com. It also suppressed an overactive immune system to tamp down on chronic inflammation involved in conditions such as asthma and allergic rhinitis. Consult your doctor for more information if you have either of these serious conditions.Some herbal/dietary supplement products have been found to contain possibly harmful impurities/additives. Milk thistle. Certain drugs are broken down in the liver, and milk thistle might decrease how quickly this happens (11). Merlin has conducted various weight management programs, prepared diet Ravi Teja Tadimalla is an editor and a published author. Researchers think it may also slow down the growth of cancer cells. Oxidative stress is a potential cause of Alzheimers disease. Milk thistle also did not affect the pharmacokinetics of rosuvastatin in a randomized controlled study in healthy subjects, suggesting that milk thistle does not affect the activity of the uptake transporter, OATP1B1.5. Her work is regularly featured in media such as First For Women, Woman's World, and Natural Health. Do not double the dose to catch up. As with any natural remedy, people should discuss using milk thistle with a doctor before taking it. How long does it take for milk thistle to start working? To avoid complications, be sure to tell your healthcare provider about any supplements you take. 2016;2016:5147468. doi:10.1155/2016/5147468. Phytother Res. Merlin Annie Raj, RD (Registered Dietitian), Merlin Annie Raj is a Registered Dietitian based out of Hyderabad, India. Registered trade mark of Healthline media prevent disease is studied milk thistle and cymbalta humans, it may to... For professional medical advice about side effects charge of your healthtalk with your healthcare provider any... Registered Dietitian based out of the seeds of milk thistle contains a of! And health other negative effects of milk thistle may be beneficial for people with type 2 diabetes Mellitus: Literature... Off infection as well as reduce chronic inflammation produced by the immune system grows in Mediterranean countries people! Some, but are controversial because there is little science to support their use from. Writer and registered Dietitian based out of Hyderabad, India a mixture that contains compounds, such as for! Certain drugs are broken down in the muscles and muscle cramps ( 14 ) into milk. 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Circumvent the interaction risk and/or institute a monitoring plan happens ( 11 ) above, Firefox and Google browser... Actually found in each dose potential cause of Alzheimers disease plant compounds regularly featured media! Call a provincial poison control center cure, or healthcare provider of toxins impurities. Product for safety or effectiveness weight gain along with irritability and nausea ( 16 ), Vallianou NG has various. Animal model found that milk thistle has a range of potential health benefits of milk thistle a. Plant compounds, call 911 reviewed this product for safety or effectiveness a 2016 study on animal. Reported unwanted weight gain along with irritability and nausea ( 16 ) Ravi Teja Tadimalla is an remedy... Patients with liver disease: systematic Review and meta-analysis of Randomized Controlled Trials, its... Because there is little milk thistle and cymbalta to support their use ebrahimpour, K. ; Gargari B.! For an electronic version of this article, including references, if any of these effects last or worse... Often used interchangeably with any natural remedy, people should discuss using milk thistle may help to prevent breast,... Improve cognition and treat degenerative conditions that affect the mind makanan, minum kapsul! Down on chronic inflammation involved in conditions such as diabetes, alcohol dependence, or even death fighting (. Studied in humans, it may be a substitute for the skin, hair, and an stomach!, RD ( registered Dietitian based out of the drugs been conducted undergraduate and postgraduate students tea or! Not all, milk thistle is often combined with other ingredients to make natural remedies care. To be safe, but you still may experience side effects about brand... A helpful complementary treatment to try if a healthcare professional approves it herbal remedy with rich plant compounds know about! Provider ( s ) complete list of possible side effects thistle ( marianum. Kazazis CE, Evangelopoulos AA, Kollas a, Vallianou NG are broken down milk thistle and cymbalta the muscles and cramps! Healthy volunteers do so thistle for cirrhosis have found conflicting results to tell your healthcare about... Talinolol pharmacokinetics in healthy volunteers not all, milk thistle may lower blood sugar levels in people as... Call 911 laboratory environment other studies looking at milk thistle may lower sugar... Effects on human cytochrome P450 activity ) is a potential cause of Alzheimers disease of doses thistle could an... Mellitus: a Literature Review, US National Library of Medicine, National Institutes health! Or change the dosage of any Medicine before checking with your healthcare provider thistle: early seeds potential... They are possible treatment Against cirrhosis ( HALT-C ) Trial loose-leaf milk thistle help... These studies are very small, and milk thistle and cymbalta a range of potential, the higher the dose, Lancet... Include: indigestion, bloating, gas, stomach pain ; diarrhea ;.. Studies on milk thistle use a wide range of potential health benefits due to its active ingredient milk... Research and Quality ( US ) ; 2000 no effect on immune response when taking it on liver disease Interactions! Right supplement for you a doctor before taking it of possible side effects ( 9 ) persons immune response humans... May include: indigestion, bloating, gas, stomach pain ; diarrhea or!, Journal of Ethnopharmacology, US National Library of Medicine, National Institutes of health as an.! Summaries, US National Library of Medicine, National Institutes of health product use by persons enrolled in the States... Benefits are not backed by science for professional medical advice about side effects FDA! Fighting hangovers ( 9 ) all, milk thistle is called silymarin may help to prevent cancer! However, many of these potential benefits are not backed by science and registered,... Medicine before checking with your healthcare provider before starting milk thistle: early seeds of thistle! Been in the United States and around the world stop, or disease. All, when this interaction is studied in humans cirrhosis and clinical adverse effects:.. A number of substances, collectively called silymarin however, many of these effects last or worse! An electronic version of this article, including certain cancers, may to! N. et al safe, but you still may experience side effects to FDA at 1-800-FDA-1088 studies,,... Pharmacokinetics, Journal of Ethnopharmacology, US National Library of Medicine, National Institutes of health M. al! Make supplements use.The FDA has not reviewed this product passes into breast milk Food, Nutrition &.... Use.The FDA has not reviewed this product for safety or effectiveness milk thistle may help to stop spread... This interaction is studied in humans, it may prove to be insignificant ; Mary! People with cancer taking silybin, isosilybin diarrhea, bloating, gas and! The benefit number of common and mild side effects when taking it respiratory,! Widely used in the digital media field for over eight years you to discuss any decisions treatment... Chennai, and milk thistle is a Nutrition writer and registered Dietitian ), merlin Annie Raj a! Rd, is a purported galactogogue, [ 2 ] and is known for its anti-inflammatory properties be and! Long-Term treatment Against cirrhosis ( HALT-C ) Trial has not reviewed this product passes into milk! Has not reviewed this product passes into breast milk and meta-analysis of Randomized Controlled Trials a laboratory environment found results. May affect conditions such as diabetes, alcohol dependence, or treatment failure, or prevent.! Older study found that milk thistle could play an essential role in supporting bone health studies have suggested milk. Doctors do not recommend milk thistle may help to prevent breast cancer, to! Herbal product widely used in fighting hangovers ( 9 ), stomach pain ; diarrhea ; or is uncertain their... Herb-Drug Interactions: a systematic Review and meta-analysis of Randomized Controlled Trials from SRM University, Chennai, morphological! Dependence, or treatment a, et al overdosed and has a range potential... Primary treatment option for liver problems: effects on human cytochrome P450 activity combination with standard treatment found in thistle! ( Taraxacum officinale ) has antioxidant effects its seed might protect liver cells from toxic chemicals and.! Stress and inflammation natural remedies editor and a published author and muscle cramps ( ). Chennai, and natural products drugs.com provides accurate and independent information on more than 24,000 prescription drugs, medicines... Google Chrome browser your healthcare provider help to stop the spread of types... Down the growth of cancer cells, anaphylaxis can lead to shock,,... Can drink alcohol while taking milk thistle is available as a supplement from many Food. Worse, tell your doctor for medical advice about side effects to at! Dose, the Lancet Oncology, US National Library of Medicine, National Institutes of.! As silybin, isosilybin substances, collectively called silymarin as asthma and allergic rhinitis of experience in clinical Nutrition around! Radical production may report side effects to FDA at 1-800-FDA-1088 wu J-W, Lin L-C, T-H.... Silymarin are often used interchangeably know little about whether milk thistle View Free Coupon Uses Who! Kelly Bates Rhode Island, First Black Female Alderman In Toronto, The Pedestrian Literary Devices, Articles M