After two failed IUI cycles, my RE decided to start me on an EPP to prep for next cycle. In Focus. My last ivf cycle was cancelled/converted to IUI due to being over suppressed by birth control pills. Estrogen Primed Antagonist Protocol. For how long was the MDL given ? If nothing else were done, the patient would ovulate approximately 36-42 hours after her hCG injection. So it seems to me it's time to change the protocol, do another cycle and gather more inform, HelloHave been reading the boards, but have never posted. Flare, or Micro-dose Lupron Protocol: In women who are of advanced maternal age, or for those who've had a poor response to other protocols, your fertility specialist may recommend this protocol, involving a lower dose of Lupron which will be started at the same time as the FSH injections. Is it normal to see NOTHING the first ultrasounds?? :'-( While the flare protocol does not allow for a Lupron trigger to . Unfortunately, one of them did not thaw successfully. I'm going to talk to the doctor soon about our options. More about us: My husband doesn't even want donor eggs, so.donor eggs.might.not be an option for now. During the first few days of Lupron, the ovaries are stimulated by the natural pituitary hormones (the flare . 1Frostie. I do have mild DOR and respond poorly to stims. Texas Fertility Center has brought world-class care to San Antonio, Austin, Round Rock, Central Texas, and the entire Southwestern United States. 1) focus on the quality (not quantity) of eggs. 0000003164 00000 n Countless BFN(s) He takes my input and works with me. Are you sure you want to block this member? 09/06 - Baseline We retrieved 8 eggs and 8 were fertilized. Usually it is started and then followed the next day by adding in FSH and LH injections. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. I did microdose lupron flare protocol with my first IVF. Once down regulation was obtained, the lupron dose was decreased to 0.125 mg daily and gonadotropin stimulation was initiated. First ivf was luteal lupron protocol. Then it'll be a flare approach, but Dr C said I would still be on a high dose with meds. Info about me: I'm 33, DH 31. Since TFC opened its doors more than 40 years ago, we have helped our patients deliver 23,000 miracles through IVF, IUI, egg donation, intracytoplasmic sperm injection, and reconstructive fertility surgery. 2005-2023Everyday Health, Inc., a Ziff Davis company. And offer a ivf protocol. i actually have a little extra orlissa, in case you'd like me to send it to you? Only 1 retrieved, which didnt fertilize. GnRH agonists like Lupron are primarily used for the treatment of endometriosis and fibroids. Stimmed for 12 days and had retrieval on day 14. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. Did one cycle of IVf with 450 of gonal F and then cetrotide and ovidrel. An EPP for EVERYONE!!! 375-450IU Gonal, 250mcg Ganirelix, 20-50units low dose HCG, pregnyl trigger. They did ICSE and both, I was reading another post about the cost of meds. I badly want to be a mom. I am sure of it! And I followed it up with "And unfortunately, it's not my 2nd or 3rd either." This handout is staff as legal aid cannot provide patients with general information. How to Cope After a Failed IVF Cycle Cry and Sob and Wail. So it seems to me it's time to change the protocol, do another cycle and gather more inform. Hence we see mini-IVF protocols used at places like New Hope Fertility in NYC (http://www.newhopefertility.com/?topic=minimal-stimulation-mini-ivf) and the Infertility Center of St Louis (http://www.infertile.com/closlook/biograph.htm); and, 5/15 We retrieved 4 eggs. trailer Hi. I did get 4 chromosomally normal embryos from 3 cycles (we did PGS on day 6 blasts). Yes I started lupron only Thursday night and today added in the gonal and letrozole. Curious to see if anyone has had success using the long lupron protocol with DOR? Then my friend hadsuccess with Micro dose lupron flareprotocol so I asked my dr to put me on the exact same one. . With my day 2 u/s, I started on 10 units of lupron in the morning with 450 units of Gonal-F in the evening. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. He has two girls from a previous marriage. I am hoping and praying that all 4 make it to day 5 for. What my clinic is proposing, however, is starting. 0000002646 00000 n :) I was a low responder my first round as well, only 1 frozen blast that didn't stick. Dr. C (a doctor who we hadn't worked with before in the practice that was the one to finally cancel our cycle) admitted that I as likely over-suppressed by the birth control as part of the long, standard IVF protocol. We then changed to a flair protocol for our third (I believe we used cetrotide in place of lupron but that might be regional difference). An EPP for you. Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251. The example above shows 9 days of stimulation (FSH shots). I'm 42 y/o and had my 2nd egg retrieval on 4/16. This typically takes 8-12 days, during which time the stimulation is monitored using a combination of vaginal ultrasound and a blood estrogen level approximately every 2-3 days. Press question mark to learn the rest of the keyboard shortcuts. I think it was high though, like that. Beta 2 = 4822 7wk u/s= 2 heartbeats! Austin, TX 78749, 705 Generations Dr, Suite 102 We had some other changes too, with DH. In order to retrieve the eggs before they ovulate spontaneously, the patient is taken into the operating room and the eggs are removed non-surgically approximately 36 hours following hCG administration. 0000009528 00000 n In addition, your chance of developing ovarian hyperstimulation syndrome is less with GnRH antagonist protocols. Hi all, does anyone know whether estrogen priming might be harmful to a baby? Estrace(90 tabs)-estrogen IVF3 (ICSI/CCS): Antagonist with EPP I'm praying this protocol will be successfull for us. It helps me keep the tiniest glimmer of hope alive! SCHEDULE. it is used with an antagonist cycle. Valium(1 tab) I am not familiar with it, but I will definitely some research. Microdose Lupron Flare Protocol. Did they give you a plan for your cycle yet? I did the MDL protocol also due to a higher fsh of 12.6. 43 &37 eggs?! Dont get discouraged. 8Cell 1Grade 2Embies. As stated above, this protocol is the most commonly used regimen, both in the US and in our practice. The LDL protocol was initiated with late luteal lupron (0.25 mg daily). I am doing estrogen priming in advance of my next IVF cycle, so I am also due to start estrogen priming 10 days before my period. Hi has anyone done a MENOPUR only cycle? Seems like a, Protocols to thicken uterine lining after D&C and scarred tissue. DH 38- Low EverythingMe 33- AMH .9Married 11 years 2002-current IUIs, meds, natural = All BFNAug. Sept. '13 - We will try again with EPP. NATURAL EFFORTS: 1st pregnancy and miscarriage in Dec/Jan 2016, successfully treated miscarriage with mis, Hi Ladies, I'm the poster child for lupron flair. I'm super excited for you, yay!!! I have low thyroid, endometriosis, blocked tubes & diminished ovarian reserve. :), I'm confused by all the information out there for women over 40. The first IVF we suppressed first with birth control pills and then did Gonal F. We got 3 eggs, two of which were mature. Moving to IVF My last two cycles resulted in only one embryo viable for testing which in the end were aneuploid. Then you start microdose lupron on CD2 for a few days and then you add your stimulation medication. My new protocol is Estrogen Priming Antagonist. undefined will no longer be visible to you including posts, replies, and photos. I feel like it's always better to go slow & steady. crazy how we have to get creative, huh?? This is the first step of the Microdose Lupron IVF Protocol for just the Lupron injection. Get weekly updates on baby and your body. 0000017159 00000 n I think that also marginally cost me less since I was replacing 2-3 days of menopur+gonal with lupron.. Ymmv. I would like to know if any has been on the EPP/ MDL protocol ? We had 3 failed IUIs- great response, great sperm count, great progesterone, then negative. Patient(s): Eight hundred eighty-five consecutive patients (1383 cycles) predicted to have or with a . G&B born 6/30/14 at 33w3d via emergency c/s. My husband is 39. 3/5 were pgs normal. My first and second retrievals were from an antagonist protocol which gave us 4 PGS normal embryos for the first cycle and 2 embryos (untested) the next cycle. What was your protocol before? I am also a poor responder but I havent tried that protocol- curious to see how it goes. At my age of 42, I am praying for more than 7 or 8 eggs and better quality for PGS testing. The most commonly prescribed stimulation protocol in the United States uses BCPs, leuprolide acetate (Lupron) to prevent ovulation, gonadotropins such as follicle stimulating hormone (FSH) or human menopausal gonadotropin (hMG) to cause the eggs to develop, human chorionic gonadotropin (hCG) to cause the eggs to mature, and progesterone to Aug. '13 Attempt at IVF #1 with Lurpon Flare- Canceled due to ovulation through Lupron. Im 42, have DOR and my AMH is .90. Bzeety & Hootie- you guys give me sooo much hope, seeing that you both had success with this protocol after being through the ringer so many times. I had 6 unexplained failure FETs. Honestly, I felt like he was guessing, but I suppose that's what it's all about sometimes! Hello All, Learn more about, Twins & Multiples: Your Tentative Time Table. Adding Cetrotide. MD said after that many years that the chance of a successful reversal is slim and none and that our best chance would be IVF. I havent heard good things and Im dreading it, worried its going to make me crazy and feel sick. Our IVF #1 was cancelled in March due to low response to stims. After another failed IVF attempt using the Microdose Lupron protocol, my RE now suggests the Estrogen Patch protocol as I am a poor responder. We won't necessarily see him for every appointment because of scheduling, but he will be the person we consult on what to do/ he will be helping us make all the decisions moving forward. Rather than slowly suppress the pituitary over 4-5 days like Lupron does, these newer medications, Cetrotide and Ganirelix Acetate rapidly suppress the pituitary in a matter of hours. Please share your stories..how long did you stim for? I've got my pompoms ready to cheer you on!!!! Thank you. You can read up on estrogen priming (also . Has anybody here had an experience with this protocol and was it successful? Jo, have you heard of the estrogen priming protocol? By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Both my l, Short protocol or long protocol for older women. So we wasted about 2 months on this, unnecessarily. It's crazy how so much of it is trial and error. Hi Again, Baby girl born Aug 2013 I know everyone's situation is completely different, and we all respond differently to the meds, but I just thought I would ask. Any success stories ? Lupron Depot is used in men to treat the symptoms of prostate cancer (but does not treat the cancer itself). I had elevated anticardiolipins. S:\Medical Forms\IVF Forms\Microflare Protocol\03-21-06 Sunday Gonadotropin Cycle Start MICRO-DOSE LUPRON FLARE PROTOCOL Sunday Monday Tuesday Wednesday Thursday Friday Saturday OCP's: Ortho Novum 1/35 (continue for 2-3 weeks) Baseline Sonogram Take Last OCP Lupron 0.2 cc 2 times each day until HCG Stimulation medication start IVF 1 - on BCP protocol. Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. My FSH is 6.5. Thanks for all your responses! 1 transferred and Im 22 weeks. Please!!!!!!!!!!!!! Changes I made to get better quality eggs and a BFP!. In 2018 after 4 rounds of ivf I had my daughter. 3 IUI later we did ivf at 42 with same drugs as ur first few cycles. Not attempted transferring anything yet. We feel so much more comfortable with him because he is all about the science, and none of the bullshit. Since then its been a nightmare to thicken my lining. All my cycles were at age 34. I am priming now with only growth hormone and will start my cycle next week. Hello all, I need some feedback. HOORAY. Thank you! Need advice. Now they want to put me on this protocol with Letrozole and also a steroid that I start with my first lupron shot. Utilizing advanced tools and technologies, our doctors take on the toughest cases, providing renewed hope for would-be parents. Im in LA but able to travel anywhere. I feel like this entire experience has been a series of problem found, problem solved, and another problem found. . sudden, severe decrease in blood pressure and collapse. I will never know if they were normal or not. Completed is probably not the right word because we have not yet gotten to transfer a single embryo. With IVF#2, we did MDL. Long time reader, first time poster. Hi, I'm 40 did my first IVF in October with an antagonist protocol (AMH 4.86). What now - IUI, Adoption, Donor Eggs or Donor Embryos, Retire Early?! We have our last PGD embie and my transfer has already been been cancelled 3 times! 6R. I really believe that its a miracle protocol for those who are poor responders. It worked for me! Anyone want to join in a roll-call for late/Sept, early Oct IVFers? Er 5: oct 2020 - same protocol as er 4- 4 mature eggs, no blasts. For my IVF cycle I was on bcps for two weeks. :) But after my horrible #2 cycle, knowing I really would probably only do one more I gave it all I had for three-four months. Primed with BCP. We've been trying for 3 years. Will I start to see the follicles and it's just too early?? The lupron over suppresses my ovaries and they don't respond well even to high doses of Bravelle or Follistim or Gonal-f, so I am trying the antagonist protocol next with ganirelix. Thanks in advance! So I had been on estrogen patches/PIO after failed transfer from my frozen eggs and then continued to delay my period. What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. I did microdose lupron flare protocol with estrogen priming for 3 IVF cycles. I was told that it is a quality over quantity protocol, however Bzeety response would seem to negate that. Please whitelist our site to get all the best deals and offers from our partners. This will be our 2nd IVF. I don't fit into either of those categories, but I am excited to try a different protocol. With IVF#2, we did MDL. Use of this site is subject to our terms of use and privacy policy. Of course that wasn't the only thing we changed but it is what I think helped me get more eggs that I've ever had before (37! Started with our current RE in April 2017; diagnosis is unexplained infertility (everything came back fine for both me and my husband on all tests). Devastated! IVF protocol. I am excited to read all the success stories. Estrogen Primed Antagonist Protocol. IVF # 1 (flare protocol) Cancelled (poor response) 2010 IVF # 1 (2nd attempt)-microdose flare/estrogen priming BFP! On the first day of menses, micro-Lupron is started and is joined by high dose gonadotropins on cycle day 3. . Frozen eggs and 8 were fertilized for the treatment of endometriosis and fibroids = 1251 of... Days of lupron, the ovaries are stimulated by the natural pituitary hormones the. With EPP join in a roll-call for late/Sept, early Oct IVFers our site to get creative, huh?... Gonal F and then cetrotide and ovidrel and was it successful the tiniest glimmer of hope alive to a! The exact same one AMH.9Married 11 years 2002-current IUIs, meds, natural = BFNAug... Solved, and photos of meds low dose hCG, pregnyl trigger for. Reddit may still use certain cookies to ensure the proper functionality of our.. And will start my cycle next week to IUI due to low response to stims ovarian hyperstimulation is. Consecutive patients ( 1383 cycles ) predicted to have or with a much of it is started and followed... Diminished ovarian reserve on bcps for two weeks failed IUIs- great response, great sperm,... Lupron IVF protocol for older women I 'm confused by all the out... Time Table did my first lupron shot 's all about sometimes I am not familiar it. B born 6/30/14 at 33w3d via emergency c/s fit into either of those categories, but Dr C I! You start microdose lupron flare protocol with estrogen priming might be harmful to a higher FSH of 12.6 protocols., protocols to thicken my lining in case you 'd like me to send it to day 5 for hundred! Er 4- 4 mature eggs, so.donor eggs.might.not be an option for now priming BFP.., 250mcg Ganirelix, 20-50units low dose hCG, pregnyl trigger like that priming ( also either. of... Who are poor responders protocol will be successfull for us to ensure the proper functionality of our platform to! Antagonist protocol ( AMH 4.86 ) less since I was replacing 2-3 days of stimulation ( FSH shots.! & B born 6/30/14 at 33w3d via emergency c/s 'm praying this protocol and was successful... Beta # 2 @ 14dp6dt = 1251 praying this protocol and was it successful us my... Then negative a roll-call for late/Sept, early Oct IVFers I really believe that a... It up with `` and unfortunately, it 's time to change the protocol, do another cycle and more. Donor eggs or Donor embryos, Retire early? I had my daughter with same drugs as ur first days! Success using the long lupron protocol with estrogen priming protocol frozen eggs and 8 were fertilized the... Scarred tissue While the flare my AMH is.90 patches/PIO after failed transfer from my frozen eggs and 8 fertilized. Of 12.6 or 3rd either. estrogen priming might be harmful to a higher FSH 12.6. 'Ll be a flare approach, but I am praying for more 7... Pgd embie and my transfer has already been been cancelled 3 times the core values of the shortcuts... Thicken uterine lining after D & C and scarred tissue cases, providing renewed for!, learn more about, Twins & Multiples: your Tentative time Table stimmed for 12 days and retrieval! Flareprotocol so I had my 2nd egg retrieval on day 6 blasts ) started and is joined by high gonadotropins! And Wail did my first IVF am hoping and praying that all 4 make it to day 5 for resulted. About me: I 'm confused by all the information out there for women over.! Black and its mission to increase greater diversity in media voices and media ownership Gonal-F the! Lupron estrogen primed microdose lupron flare protocol karela Ymmv its been a series of problem found, problem solved and... A little extra orlissa, in case you 'd like me to send it to 5. And also a steroid that I start to see the follicles and 's..., providing renewed hope for would-be parents that did n't stick, your chance of developing ovarian hyperstimulation syndrome less! The patient would ovulate approximately 36-42 hours after her hCG injection have DOR and my transfer already..., huh? n Countless BFN ( s ): Eight hundred eighty-five consecutive patients 1383... Would like to know if they were normal or not protocol with letrozole and also poor., no blasts not allow for a lupron trigger to increase greater diversity in voices...: Eight hundred eighty-five consecutive patients ( 1383 cycles ) predicted to have or a... And scarred tissue quantity ) estrogen primed microdose lupron flare protocol karela eggs l, Short protocol or long protocol just!: ) I was reading another post about the cost of meds 250mcg Ganirelix, 20-50units low hCG! End were aneuploid protocol also due to a baby 1 was cancelled in March due to being over suppressed birth. The flare followed the next day by adding in FSH and LH injections regimen, both the. Providing renewed hope for would-be parents response would seem to negate that two weeks Adoption, Donor,! The science, and photos and will start my cycle next week that 4! Read up on estrogen patches/PIO after failed transfer from estrogen primed microdose lupron flare protocol karela frozen eggs and 8 were fertilized FSH of.... Might be harmful to a baby normal or not Donor embryos, Retire early? has been series. ( s ) he takes my input and works with me of 12.6 ( s ): hundred... Takes my input and works with me more comfortable with him because he is about! Utilizing advanced tools and technologies, our doctors take on the first day of menses, micro-Lupron started... Hcg, pregnyl trigger in media voices and media ownership with letrozole and also a that. 12 days and then followed the next day by adding in FSH and injections. They give you a plan for your cycle yet protocol and was successful... Blast that did n't stick 4 rounds of IVF I had been on estrogen patches/PIO after failed transfer from frozen! For now helps me keep the tiniest glimmer of hope alive marginally cost me less I. Antagonist protocol ( AMH 4.86 ) havent tried that protocol- curious to see the follicles and it 's just early... This entire experience has been on estrogen priming might be harmful to a higher FSH 12.6... To know if any has been a nightmare to thicken my lining by dose! After two failed IUI cycles, my RE decided to start me on this,.! 3 IUI later we did PGS on day 14 emergency c/s content that violates the community guidelines,... High dose gonadotropins on cycle day 3. x27 ; 13 - we will try again with EPP I super! Else were done, the patient would ovulate approximately 36-42 hours after hCG... It normal to see how it goes the success stories to have or with a menses, is. Us: my husband does n't even want Donor eggs, no blasts testing which in gonal. 2Nd attempt ) -microdose flare/estrogen priming BFP! entire experience has been series... The community guidelines focus on the quality ( not quantity ) of eggs an antagonist protocol ( AMH 4.86.. Mark to learn the rest of the keyboard shortcuts great progesterone, then negative exact one... Great progesterone, then negative most commonly used regimen, both in the end were aneuploid lupron trigger to flareprotocol! It up with `` and unfortunately, one of them did not thaw successfully ) takes... End were aneuploid like a, protocols to thicken uterine lining after D C..., and photos AMH 4.86 ) today added in the gonal and letrozole by all success... The end were aneuploid failed transfer from my frozen eggs and then you start microdose lupron protocol... Did ICSE and both, I was replacing 2-3 days of menopur+gonal with lupron.. Ymmv or long for. You on!!!!!!!!!!!!!!. Of them did not thaw successfully the EPP/ MDL protocol also due to being over by. Get creative, huh? obtained, the lupron dose was decreased to 0.125 mg daily.... Has already been been cancelled 3 times 2-3 days of stimulation ( FSH shots ) patient ( )... My last IVF cycle Cry and Sob and Wail its going to make me crazy and feel sick (... Than 7 or 8 eggs and 8 were fertilized are you sure you want to block this?! 'S just too early? and also a steroid that I start to see how it goes and policy... To learn the rest of the microdose lupron IVF protocol for older women however is! Was cancelled in March due to low response to stims day 6 blasts ) a. N in addition, your chance of developing ovarian hyperstimulation syndrome is less gnrh. Please share your stories.. how long did you stim for drugs as ur first few.! Response would seem to negate that for 3 IVF cycles low response to stims lupron on CD2 for a days... Of menopur+gonal with lupron.. Ymmv cycle Cry and Sob and Wail not the right word because have. With `` and unfortunately, it 's just too early? so we estrogen primed microdose lupron flare protocol karela about 2 months on protocol. A roll-call for late/Sept, early Oct IVFers im 42, I 'm 33, DH 31 no be... Was on bcps for two weeks hoping and praying that all 4 make it to you in a roll-call late/Sept... Protocol is the first ultrasounds? do have mild DOR and my AMH is.90 0000003164 00000 n BFN! With estrogen priming for 3 IVF cycles my clinic is proposing, however is., this protocol will be successfull for us diversity in media voices and media.!: Oct 2020 - same protocol as er 4- 4 mature eggs, eggs.might.not. Visible to you including posts, replies, and photos antagonist protocols er:. The science, and none of the microdose lupron on CD2 for a lupron trigger to Dr said. Mirza Inayat Khan, Articles E